Director:
Univ.-Prof. Dr. Beatrix Grubeck-Loebenstein
Rennweg 10
A-6020 Innsbruck
Phone: +43 512 583919
Fax: +43 512 583919 8
Email: iba(at)oeaw.ac.at
Dr. Dr.med. Andrea B. Maier (MD, PhD)
Leiden University Medical Center, Department of Gerontology and Geriatrics
"The phenotype of longevity; translational research from clinical to cellular characteristics.”
ao.Univ.-Prof. Dr.med.univ. Michael Schirmer
Univ.-Klinik für Innere Medizin I, Medizinische Universität Innsbruck
"Pro-inflammatory T-helper cells: NKG2D-stimulation and pro-apoptotic effects of ATG"
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Am 28.04.2012 fand am IBA die Lange Nacht der Forschung statt.
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IBA scientists will organize a high-calibre scientific symposium on molecular mechanisms of aging in February 2013
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Link: www.ncbi.nlm.nih.gov/pubmed
Andrea Taferner was awarded a EMBO Short-term Fellowship in order to support her scientific stay in Heraklion (Crete, Greece).
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IBA researchers have discovered that upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8+ T cells sensitizing them to apoptotic cell death. www.ncbi.nlm.nih.gov/pubmed/22435726
IBA researchers (Mitterberger et al., 2012) discovered in collaboration with the research group of Rodney L. Levine (National Institutes of Health, Bethesda, USA) a novel function of Carbonic anhydrase III (CAIII), a enzyme acting as antioxidant in fat tissue. They showed that CAIII is a regulator of adipogenesis in adipocyte progenitor cells.
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Mesenchymal stem cell (MSC) differentiation capacity changes during aging which in due course results in attenuated regeneration thus yielding impaired bone healing and/or remodelling after injury or illness.
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Best wishes for their daughter Leni, who was born on January 10th 2012!
Article in ASBMB today
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